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Avanafil, known by its brand name Stendra, is yet another member of the PDE5 inhibitor class of erectile dysfunction medications. What sets this option apart from others in the class is its shortest onset of action—as soon as 15 minutes after taking it. Avanafil is also the least likely of members of this drug class to cause stomach upset or dyspepsia.

Easily the most common Tadalafil side effect is a mild to moderate headache. Tadalafil works by increasing blood flow, which causes blood vessels to dilate. This increased &amp