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Manufacture and sale of sildenafil citrate drugs is common in China, where Pfizer's patent claim is not widely enforced. Sildenafil protects cyclic guanosine monophosphate (cGMP) from degradation by cGMP-specific phosphodiesterase type 5 (PDE5) in the corpus cavernosum. The pharmacokinetics of sildenafil in patients with severely impaired hepatic function have not been studied. Maximum observed plasma concentrations are reached within 30 to 120 minutes (median 60 minutes) of oral dosing in the fasted state.
The safety and effectiveness of Viagra haven’t been studied in people of this age group. Before starting Viagra, talk with your doctor about any blood pressure problems you have. If you have high blood pressure that’s managed with medication, your doctor may prescribe a dose of Viagra for you that’s lower than the typical dose. Viagra is a brand-name drug, while sildenafil is a generic form of Viagra.
The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so. Before taking sildenafil, tell your doctor or pharmacist if you are allergic to it