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Take this medication about 30 minutes before sexual activity, or when your doctor recommends. As research into female Viagra is limited and the effects of taking the drug are not well established, Viagra isn’t recommended for FSD and it’s not a good idea to take it. However, there are a number of safe, medically approved alternatives that could help improve your sexual function.

As with any drug, never change your dosage of Viagra without your doctor’s recommendation. If you have questions about the dosage of Viagra that’s right for you, talk with your doctor. Doing this can increase your risk for serious side effects. Due to age-differences in plasma protein binding, the corresponding increase in free sildenafil plasma concentration was approximately 40%. In healthy volunteers receiving sildenafil (100 mg single dose), less than 0.0002% (average 188 ng) of the administered dose was present in ejaculate 90 minutes after dosing.

In order to minimise the potential for developing postural hypotension, patients should be hemodynamically stable on alpha-blocker therapy prior to initiating sildenafil treatment. Initiation of sildenafil at a dose of 25 mg should be considered (see section 4.2). In addition, physicians should advise patients what to do in the event of postural hypotensive symptoms. Viagra is approved to treat erectile dysfunction (ED) in males. But you may have questions about whether Viagra can be used in females. Or you may be wondering if there’s a drug similar to Viagra that can help females with sexual dysfunction.

A dose of Viagra will completely leave your system within about 20 to 24 hours. A doctor may adjust someone’s dosage of Viagra based on their age and medical history. For example, men older than 65 or those with hepatic or renal impairment are typically given a starting dose of 25 mg. The standard dose of Viagra for ED is 50 mg taken as needed, about one hour before sexual activity. According to manufacturer instructions, Viagra should only be taken once per day on an as-needed basis unless otherwise advised by a doctor.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. This medicine usually begins to work for erectile dysfunction within 30 minutes after taking it. It continues to work for up to 4 hours, although its action is usually less after 2 hours. For sildenafil to work properly, you'll need to be sexually excited.

We are supported by leaders in the Canadian pharmacology and specialized medical fields. Felix adheres strictly to all the regulations set forth by all applicable Colleges of Pharmacists and Colleges of Physicians and Surgeons in which we operate. The only way to buy sildenafil online in Canada is to first get a prescription from a licensed healthcare practitioner. The only way to get a sildenafil or viagra prescription in Canada is to first speak with a licensed healthcare practitioner (like the ones at Felix). Just complete an online assessment, and if your healthcare practitioner believes that sildenafil is the right choice for you, they can write you a prescription for it. It is also strongly recommended that you keep an up-to-date list of all the medications you take and carry it with you at all times.

On average across all three doses, Viagra takes 30 minutes to 1 hour to start working. Higher doses take slightly longer to reach their maximum strength inside your body, but this difference is fairly small. However, the dose can be increased to 100mg or lowered to 25mg based on how it works for you. Take Sildenafil about 4 hours before having sex for best results. If after eight attempts Sildenafil 50mg still doesn't provide the desired results, consult your doctor about adjusting the dosage or exploring alternative medications like Tadalafil (Cialis). Always consult your doctor before making any changes to your treatment.

Single doses of antacid (magnesium hydroxide/aluminum hydroxide) did not affect the bioavailability of VIAGRA. Although the interaction between other protease inhibitors and sildenafil has not been studied, their concomitant use is expected to increase sildenafil levels. Cimetidine (800 mg), a nonspecific CYP inhibitor, caused a 56% increase in plasma sildenafil concentrations when co-administered with VIAGRA (50 mg) to healthy volunteers. In addition, N-desmethyl metabolite AUC and Cmax values significantly increased by 200% and 79%, respectively in subjects with severe renal impairment compared to subjects with normal renal function. The mean profiles of the change from baseline in standing systolic blood pressure in subjects treated with doxazosin in combination with 100 mg VIAGRA or matching placebo are shown in Figure 4.

The major circulating metabolite results from N-demethylation of sildenafil. This metabolite has a phosphodiesterase selectivity profile similar to sildenafil and an in vitro potency for PDE5 approximately 50% that of the parent drug. Plasma concentrations of this metabolite are approximately 40% of those seen for sildenafil. The N-desmethyl metabolite is further metabolised, with a terminal half-life of approximately 4 h. When sildenafil is taken with food, the rate of absorption is reduced with a mean delay in tmax of 60 minutes and a mean reduction in Cmax of 29%. In cases of overdose, standard supportive measures should be adopted as required.

The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so. Before taking sildenafil, tell your doctor or pharmacist if you are allergic to it